Bacterial Vaginosis and Colonization by Gardnerella Vaginalis in Pregnant Women at Mother-Child University Hospital Centre Antananarivo between 2017 And 2018

Zakasoa Mbololona RAVAOARISAINA, Vonitsoa Lalaina RAHAJAMANANA, Prisca Nivohanta RAKOTONIRINA, Andry Maharo ANDRIANARIVELO, Andry RASAMINDRAKOTROKA

Abstract


Background: There was no study about bacterial vaginosis and colonization by Gardnerella vaginalis in pregnant women at Ambohimiandra Mother and Child Hospital Antananarivo.

Objective: To determine the prevalence of bacterial vaginosis and colonization by Gardnerella vaginalis in pregnant women at Ambohimiandra Mother-Child Hospital and to raise awareness about the value of bacteriological examination of vaginal secretions in pregnant women in developing countries to avoid infectious complications during pregnancy.

Materials and methods: This is an observational study conducted at Ambohimiandra Mother-Child Hospital between August 2017 and August 2018. All pregnant women carrying out a systematic bacteriological examination of vaginal sampling at the laboratory of this hospital university were included.

Results: During the study, 130 pregnant women were realized a systematic bacteriological examination of vaginal sampling. Among of these, 30.76% had bacterial vaginosis and 11.53% were colonized with Gardnerella vaginalis. These cases were encountered in pregnant women at the 2nd and 3rd trimester.

Conclusion: We describe the frequency of bacterial vaginosis and colonization by Gardnerella vaginalis during pregnancy in women with no complication at the time of sampling, finding a high frequency of bacterial vaginosis and a considerable rate of Gardnerella vaginalis carriage.

Keywords - Bacterial vaginosis; Gardnerella vaginalis; Infectious; Pregnancy; Antananarivo.

Keywords


Bacterial vaginosis; Gardnerella vaginalis; Infectious; Pregnancy; Antananarivo.

Full Text:

PDF

References


Holzman C, Levanthal JM, Qiu H, Jones NM, Wang J. (2001). The Bacterial Vaginosis Study Group. Factors linked to Bacterial Vaginosis in Non-pregnant Women. Am J Public Health, 19(10): 1664-1670.

Adad SJ, De lima RV, Sawan ZT, Slive ML, de Souza MA, Saldanha JC, et al. (2001). Frequency of Trichomonas vaginalis, Candida spp. and Gardnerella vaginalis in cervical vaginal smears in four different decades. Sao Paulo Med J, 119(6), 200–205.

Hillier SL, Nugent RP, Eschenbach DA, Krohn MA, Gibbs RS, Martin DH et coll. (1995). For the Vaginal Infections and Prematurity Study Group. « Association between bacterial vaginosis and preterm delivery of a low-birth-weight infant », N Engl J Med, 333, 1737–1742.

Gravett MG, Hammel D, Eschenbach DA, Holmes KK. (1986). « Preterm labor associated with subclinical amniotic fluid infection and with bacterial vaginosis », Obstet Gynecol, 67, 229–237.

Leitich H, Bodner-Adler B, Brunbauer M, Kaider A, Egarter C, Husslein P. (2003). « Bacterial vaginosis as a risk factor for preterm delivery: a meta-analysis », Am J Obstet Gynecol, 189, 139–147.

Watts DH, Krohn MA, Hillier SL, Eschenbach DA. (1990). « Bacterial vaginosis as a risk factor for postcesarean endometritis », Obstet Gynecol, 75, 52–58.

Soper DE, Bump RC, Hunt WG. (1990). « Bacterial vaginosis and trichomonas vaginitis are risk factors for cuff cellulites after abdominal hysterectomy », Am J Obstet Gynecol, 163, 1016–1023.

Cohen J. (2000). HIV Transmission – AIDS researchers look to Africa for new insights. Science, 287, 942.

Eckert LO, Hawes SE, Stevens CE, Koutsky LA, Eschen-bach DA, Holmes KK. (1998) . Vulvovaginal candidiasis: clinical manifestations, risk factors, management algorithm. Ob-stet Gynecol, 92(5), 757–765.

El Ahmed HH, Cañadas-De la Fuente GA, Fernández- Castillo R, González-Jiménez E, Cantero-Hinojosa J, Lardón-Fernández M. (2012). Generalized cutaneous candidiasis in newborn at term. Biomedica. 32(2), 170–173.

Fidel PL Jr. (1999). Host defense against oropharyngeal and vaginal candidiasis: site-specific differences. Rev Iberoam Micol. 16(1), 8–15.

Molero G, Diez-Orejas R, Navarro-Garcia F, Monteolive L, Pla J, Gill C, et al. (1998). Candida albicans: genetics, dimorphism and pathogenicity. Int Microbiol. 1(1), 95–106.

Nelson DB, Macones G. (2002). Bacterial vaginosis in pregnancy: current findings and future directions. Epidemiol Rev, 24(2), 102–108.

Coleman JS, Gaydos CA, Witter F. (2013).Trichomonas vaginalisvaginitis in obstetrics and gynecology practice: new con-cepts and controversies. Obstet Gynecol Surv, 68(1), 43–50.

Saporiti AM, Gomez D, Levalle S, Galeano M, Davel G, Vivot W, et al. (2001). Vaginal candidiasis: etiology and sensitivity profile to antifungal agents in clinical use. Rev Argent Microbiol, 33(4), 217–222.

Sanusi Mohammed Ibrahim, Mohammed Bukar and Bala Mohammed Audu. (2016). Management of Abnormal Vaginal Discharge in Pregnancy, Genital Infections and Infertility, Atef M. Darwish, IntechOpen. [Accessed May 20, 2019]. Available from: https://www.intechopen.com/books/genital-infections-and-infertility/management-of-abnormal-vaginal-discharge-in-pregnancy#B5.

Upcroft P, Upcroft JA. (2001). Drug targets and mechanism of resistance in the anaerobic protozoa. Clin Microbiol Rev, 14, 150–154.

Akinbiyi AA, Watson R, Feyi-Waboso P. (2008). Prevalence of Candida albicans and bacterial vaginosis in asymptomatic pregnant women in South Yorkshire, United Kingdom: outcome of a prospective study. Arch Gynecol Obstet, 278:463–466.

Machado D, Joana C et al. (2017). Prevalence of bacterial vaginosis in Portuguese pregnant women and vaginal colonization by Gardnerella vaginalis. Peer J, 5:e3750.

Hyman RW, Fukushima M, Jiang H, Fung E, Rand L, Johnson B, Vo KC, Caughey AB, Hilton JF, Davis RW, Giudice LC. (2014). Diversity of the vaginal microbiome correlates with preterm birth. Reprod Sci, 21(1):32–40.

Jespers V, Van de Wijgert J, Cools P, Verhelst R, Verstraelen H, Delany-Moretlwe S,Mwaura M, Ndayisaba GF, Mandaliya K, Menten J, Hardy L, Crucitti T. (2015). Vaginal Biomarkers Study Group. The significance of Lactobacillus crispatus and L. vaginalis for vaginal health and the negative effect of recent sex: a cross-sectional descriptive study across groups of African women. BMC Infectious Diseases, 15:115.

Aroutcheva AA, Simoes JA, Behbakht K, Faro S. (2001). Gardnerella vaginalis isolated from patients with bacterial vaginosis and from patients with healthy vaginal ecosystems. Clin Infect Dis, 33:1022–1027.


Refbacks

  • There are currently no refbacks.


Copyright (c) 2019 ZAKASOA MBOLOLONA RAVAOARISAINA

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.