Bismuth and Its Wide Applications

Ayodele Temidayo Odularu

Abstract


Abstract

This review describes the coining of the name of bismuth, recognition as an element from chemists and its main oxidation states. Its  stability when it forms compounds and the relevance to chemotherapy due to high effectiveness and none to low level toxic profile. In modern medicine, the use of bismuth(III) is seen in nuclear medicine, anticancer, antitumor and antimicrobial studies. The challenge of bismuth(V) not to be stable in aqueous solution has made it to be less considered than bismuth(III).

Keywords: Bismuth, bismuth(III), bismuth(V), anticancer, antimicrobial studies.


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References


References

N. Yang and H. Sun,”Biocoordination Chemistry of Bismuth: Recent Advances,” Coordination Chemistry Review, vol. 251, pp. 2354-2366, 2007.

P. J. Sadler, H. Li and H. Su, Coordination Chemistry of Metals in Medicine: Target Sites for Bismuth. Coordination Chemistry Review, vol. 185-186, pp. 689-709, 2009.

V. Stavila, R. L. Davidovich, A.; Gulea, K. H. Whitmire and K. H. Bismuth(III) Complexes with Aminopolycarboxylate and Polyaminopolycarboxylate Ligands: Chemistry and Structure. Coordination Chemistry Review vol. 250, pp. 2782-2810, 2006.

D. M. Keogan and D. W. Griffith,” Current and Potential Applications of Bismuth-Based Drugs,” Molecules, vol. 19, pp. 15258-15297.

H. Li, C. S. Lai, J. Wu, P. C. Ho, D. Vos and E. R. T. Tiekink, “Cytotoxicity, Qualitative Structure-Activity Relationship (QSAR), and Anti-tumor Activity of Bismuth Dithiocarbamate Complexes,” Journal of Inorganic Biochemistry, vol. 101, no. 5, pp. 809-816, 2007.

V. K. Tiwari, S. K. Shukla, V. S. Chauhan, R. Kant, R. Sushma, I C. Tewari, “Antimicrobial, antitumour and Gastroprotective Studies of Some New Water Soluble Organic Derivatives of Bismuth,” International Journal of Pharmaceuticals Analysis, vol. 2, 9-14, 2010.

B. Desoize, " Metals and Metal Compounds in Cancer Treatment,” Anticancer Research, vol. 24, no. 3a, pp. 1529-1544, 2004.

J. M. Bothwell, S. W. Krabbez and R. S. Mohan, “Applications of Bismuth (III) Compounds in Organic Synthesis,” Chemical Society Reviews vol. 40, pp. 4649-4707, 2011.

J. A. R. Salvador, R. M. A. Pinto and S. M. Silvestre,” Recent Advances of Bismuth(III) Salts in Organic Chemistry: Application to the Synthesis of Aliphatics, Alicyclics, Aromatics, Amino Acids and Peptides, Terpenes and Steroids of Pharmaceutical Interest,” Mini-Reviews in Organic Chemistry, vol. 6, pp. 241-174, 2009.

J. A. R. Salvador, R. M. A. Pinto and S. M. Silvestre,” Applications of Bismuth(III) Reagents and Catalysts to the Heterocyclic Compounds of Pharmaceutical Interest, In: Atta-ur-Rahman (Ed).Advances in Organic Synthesis, Beijing: Bentham Sci. Pub., pp. 64-181, 2015.

Q. Zang, G. Zhong and Y. Zhang, Synthesis, “Characterization and Thermal Decomposition of Bismuth(III) Ternary Complexes of Phthalate,” Journal of Chemical and Pharmaceutical Research, vol. 6, no. 10, pp. 794-799, 2014.


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